TABLE 4.

Known host genes whose expression is changed the hippocampus of LCMV-cgPi mice^a

GenBank accession no.	LCMV-cgPi signalb	Mock signalb	Signal ratio	P	Gene identityc
AW047653	206.3	6.2	33.27	0.000002	UBP43
U43086	493.6	34.8	14.18	0.000001	GARG-49
U43084	454	39.6	11.46	0.000001	GARG-16
X56602	377.2	42.1	8.96	0.000001	ISG15
D90146	122	16.6	7.35	0.000533	MHCI Q8/9d
M27134	176.3	24.9	7.08	0.000085	MHCI K region locus 2
U06924	330.8	49.3	6.71	0.000001	STAT1
X16202	892.1	195	4.57	0.000001	MHCI Q4
U55060	234.2	57.2	4.09	0.000054	β-Gal binding lectin
X67809	892.2	233.1	3.83	0.000001	Peptidylprolyl isomerase C-associated protein
D63902	119.6	31.6	3.78	0.000004	Zinc finger protein 147
U43085	121	33.1	3.66	0.000253	GARG-39
U19119	193	55.2	3.50	0.000001	LRG-47
AJ007972	265.7	76.3	3.48	0.000021	GTPI
X01838	3369.6	989.1	3.41	0.000001	Beta-2 microglobulin
U51992	502.5	157.2	3.20	0.000001	IRF-9
L12367	34.6	215.1	−6.22	0.000074	Adenylyl cyclase-associated protein
V00727	80.5	321.9	−4.00	0.001304	FBJ osteosarcoma oncogene

^aKnown host genes with altered expression in hippocampal tissue of LCMV-cgPi mice. Hippocampus tissue was pooled from age- and sex-matched LCMV-cgPi mice (n = 10) with virus titers of 10⁴ to 10⁵ PFU/ml and from control mice (Mock) (n = 10), and total RNAs were isolated and used for gene profiling studies using Affymetrix murine genomic DNA array U74Av2. Genes were identified as described for Table 3. Displayed are the known host genes that showed consistent regulation differences of >3-fold between LCMV-cgPi mice and controls. The mean fluorescence intensities for each probe set and the signal ratios with corresponding P values of changes are indicated.

^bFluorescence units (intensity).

^cMHCI, major histocompatibility complex class I; β-Gal, β-galactosidase.