FIG. 3.

T2 protects against TNFR1-induced cell death. Survival of HEK 293T cells 48 h posttransfection with pcDNA3-TNFR1 and pcDNA3-M-T2myc or pcDNA3-M-T2ΔPLADmyc together with LacZ, and other control plasmids, as indicated. Viability was determined by measuring β-galactosidase activity in surviving cells. Data shown are means ± the standard errors of the means of triplicate transfections, each measured in quadruplicate, and are representative of repeated assays. An asterisk indicates a statistically significant difference (P < 0.05). (Insert) Western immunoblot detection of M-T2myc and M-T2ΔPLADmyc in transfected HEK 293T cells.