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Rapamycin abolishes the resistance of Rh30 and CTR rhabdomyosarcoma cells to cisplatin-induced apoptosis. Rh30 and CTR cells were pretreated with rapamycin (100 nM) for 3 hours and then treated with cisplatin (25 µM) for 48 hours in 10% FBS medium. Cells were examined and photographed under light microscope at 200x. The results were representative of three independent experiments.
