TABLE 1.

Summary of OB-fold protein complexes

Structure	Ligand	PDB code (bound)	Nucleic acid polarity	Buried surface area (Å)a	nt/OB- foldb	Free structure
RPA70	ssDNA	1JMC, 2.4 Å	DBD-A: standard	560	3	1FGU
			DBD-B: standard	572	5
EcSSB	ssDNA	1EYG, 2.8 Å	Reverse	1754	18	1QVC
EcRho	ssRNA	2A8V, 2.4 Å	Standard	351	2	1A8V
				379	2
OnTEBP	Spec. ssDNA	1JB7, 1.86 Å	α1: standard	718c	10	1K8G
		1KIX, 2.7 Å	α2: standard, + 3′-turn	723c	8	α N35
		1K8G, 2.6 Å	β: reverse	272c	2
Cdc13	Spec. ssDNA	1KXLd, NMR	Standard	1321	11	-
EcAspRS	tRNAasp anticodon	1ASZ (S. cerevisiae) 3.0 Å, inc. ATP	Standard	870e	8	1EQR
		1ASY (S. cerevisiae) 3.0 Å
		1C0A (E. coli) 2.4 Å, inc. AMP
ScAspRS	Junction DNA	1GM5, 3.24 Å	Standard	569	4	-
RecG	23S rRNA	1JJ2, chain A, 2.4 Å	Standard	302	4	1RL2
L2	16S rRNA	1J5E, chain L, 3.05 Å	NA-only binds helices	1577	22	-
S12	16S rRNA	1J5E, chain Q, 3.05 Å	Standard, helices excluded	1966	31	1RIP
S17	16S rRNA	1HR0, chain W, 3.2 Å	Standard	839	10	1AH9

^aBSA =[ASA(OB-fold + nucleic acid)-ASA(OB-fold)-ASA (nucleic acid) ]=2, calculated using NACCESS v.2.1.1 with a probe size of 1.5 Å. ASA =solvent accessible surface area.

^bOnly nucleotides that are within 3.5 Å of the canonical OB-fold.

^cFor 1JB7 structure of ternary complex.

^dPlus unpublished models w/ DNA.

^eFor E. coli AspRS.