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. 2006 Sep 15;2(9):e92. doi: 10.1371/journal.ppat.0020092

Figure 6. Plasma Levels of sVEGFR-3 of Microfilaremic Patients before and 12 Mo after Doxycycline Treatment.

Figure 6

Plasma concentrations (mean ± SD) of sVEGFR-3 were measured from plasma of microfilaremic patients before and 12 mo after doxycycline treatment (17 doxycycline treated, 16 placebo, see Table 1). The sVEGFR-3 levels decreased significantly at 12 mo (preceding supratesticular lymphatic dilation, see Table 2) in the doxycycline-treated patients (p = 0.0125) to a level close to that of endemic controls whereas there was no difference in the placebo group (paired t-test).