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. Author manuscript; available in PMC: 2006 Sep 14.
Published in final edited form as: Mol Ther. 2006 May 19;14(1):45–53. doi: 10.1016/j.ymthe.2006.03.014

FIG. 1.

FIG. 1

Plasma hF.IX levels in mice following injection of hF.IX-expressing rAAV8 or 9 vector via four different routes. Adult male (M) or female (F) C57BL/6 mice were injected with 8.0 × 1010 vg/ mouse of AAV8- or 9-hF.IX16 via portal vein (PV), tail vein (TV), intraperitoneal (IP), or subcutaneous (SC) injection. Combinations of serotype–vector administration route–animal sex are indicated. Plasma hF.IX levels were determined 1 day, 4 days, and 1, 2, 4, 6, 8, and 12 weeks postinjection and are shown as a bar graph with means ± standard deviations (n = 3–5 each).