Gene organization of actinomycete plasmids. All plasmids are drawn starting from the GntR-type regulatory gene. Identical colors indicate similar function. Red, GntR-type regulator; yellow, spread genes; orange, spdB2; blue, tra; white, Orf; grey, replication gene; light red, regulatory gene; pink, mutT homologue; green, integration/excision/recombination gene; brown, transposon. Arrows indicate regions with promoter activity. (A) Streptomyces RCR plasmids. (B) Non-RCR-type actinomycete plasmids. Only the putative transfer region of the 356-kb linear SCP1 plasmid is shown. GenBank/EMBL accession numbers: pSG5, X80774; pSVH1, Muth (unpublished); pIJ101, M21778; pSB24.2, M32513; pJV1, U23762; pSN22, D14281; pSNA1, AJ243257; pSAM2, AJ005260; pSA1.1, AB010724; pMEA300, L36679; SCP2 AL645771; and SCP1, AL590463.