TABLE 1.
Correlation between nucleotide sequence identity of PRRSV isolates and HMA results when Ingelvac PRRS MLV and Ingelvac PRRS ATP vaccines were used as reference strains
| Isolate no. | Origina | Ingelvac PRRS MLV
|
Ingelvac PRRS ATP
|
||||
|---|---|---|---|---|---|---|---|
| Nucleotide sequence identity (%) | HMA resultb | After vaccine introduced | Nucleotide sequence identity (%) | HMA result | After vaccine introduced | ||
| Ingelvac PRRS MLV | BIVI | 100 | + | 89 | − | N | |
| VR2332 | BIVI | 99 | + | N | 90 | − | N |
| 27011-01 | ISUVDL | 99 | + | Y | 89 | − | N |
| 44010-01 | ISUVDL | 99 | + | Y | 90 | − | N |
| 47450-01 | ISUVDL | 99 | + | Y | 90 | − | N |
| 16727-01 | ISUVDL | 99 | + | Y | 89 | − | N |
| 18571A-01 | ISUVDL | 99 | + | Y | 89 | − | N |
| 93-41462 | NVSL | 99 | + | N | 89 | − | N |
| 19139-01 | ISUVDL | 98 | + | Y | 89 | − | N |
| 21373A-01 | ISUVDL | 98 | + | Y | 89 | − | N |
| 18087B-01 | ISUVDL | 98 | + | Y | 89 | − | N |
| 30603-22-01 | ISUVDL | 97 | − | Y | 88 | − | N |
| 12711-3-01 | ISUVDL | 97 | − | Y | 89 | − | N |
| ISU22 | ISUPSP | 97 | − | N | 89 | − | N |
| PDV9502 | NVSL | 97 | − | N | 91 | − | N |
| 98-37120-2 | ∗NVSL | 97 | − | Y | 89 | − | N |
| 15102 44.43 | ISUVDL | 96 | − | Y | 88 | − | N |
| ISU1894 | ISUPSP | 96 | − | N | 89 | − | N |
| 93-4506 | NVSL | 96 | − | N | 89 | − | N |
| 98-27687 | ∗NVSL | 96 | − | Y | 89 | − | N |
| 35019-01 | ISUVDL | 95 | − | Y | 88 | − | N |
| 18070-01 | ISUVDL | 95 | − | Y | 87 | − | N |
| ISU79 | ISUPSP | 94 | − | N | 88 | − | N |
| ISU30262 | ISUPSP | 93 | − | N | 90 | − | N |
| 89-47361 | NVSL | 93 | − | N | 90 | − | N |
| 89-46489 | NVSL | 93 | − | N | 90 | − | N |
| 89-47363 | NVSL | 93 | − | N | 90 | − | N |
| ISU28 | ISUPSP | 92 | − | N | 90 | − | N |
| 93-30352 | NVSL | 92 | − | N | 92 | − | N |
| 1765-2-01 | ISUVDL | 91 | − | Y | 88 | − | N |
| ISU 3927 | ISUPSP | 91 | − | N | 91 | − | N |
| ISU33 | ISUPSP | 91 | − | N | 88 | − | N |
| 92-1205 | NVSL | 91 | − | N | 87 | − | N |
| 93-36048 | NVSL | 91 | − | N | 89 | − | N |
| 93-45010 | NVSL | 91 | − | N | 91 | − | N |
| ISU55 | ISUPSP | 91 | − | N | 89 | − | N |
| ISU4 | ISUPSP | 91 | − | N | 91 | − | N |
| 98-21995-1 | ∗NVSL | 90 | − | Y | 95 | − | N |
| 98-31701 | ∗NVSL | 90 | − | Y | 91 | − | N |
| 97-27796-4 | ∗NVSL | 90 | − | Y | 96 | − | N |
| JA142 | BIVI | 90 | − | Y | 99 | + | N |
| Ingelvac PRRS ATP | BIVI | 89 | − | Y | 100 | + | |
| 4519-01 | ISUVDL | 89 | − | Y | 88 | − | N |
| 97-27796-2 | ∗NVSL | 89 | − | Y | 90 | − | N |
| 98-5579 | ∗NVSL | 89 | − | Y | 91 | − | N |
| 98-4236 | ∗NVSL | 89 | − | Y | 90 | − | N |
| VR2385 | ISUPSP | 89 | − | N | 89 | − | N |
| 98-13795-3 | ∗NVSL | 88 | − | Y | 90 | − | N |
| 98-6470 | ∗NVSL | 88 | − | Y | 89 | − | N |
| 98-13795-1 | ∗NVSL | 88 | − | Y | 89 | − | N |
| 98-13795-5 | ∗NVSL | 88 | − | Y | 90 | − | N |
| 98-13795-10 | ∗NVSL | 88 | − | Y | 90 | − | N |
| 98-13795-13 | ∗NVSL | 88 | − | Y | 90 | − | N |
a
BIVI, Boehringer Ingelheim Vetmedica, Inc. Ames, Iowa; ISUVDL, Iowa State University's Veterinary Diagnostic Laboratory, Ames, Iowa; ISUPSP, Prem S. Paul (while he was at Iowa State University, Ames, Iowa); NVSL, National Veterinary Services Laboratories, Ames, Iowa (acute PRRS isolates indicated with ∗).
b
+, homoduplex; −, heteroduplex.