TABLE 5.
MICs of 17 antimicrobial agents for 15 strains of A. sanguinicola
| Antimicrobial drug (cancer range, μg/ml) | No. of strains for which MIC (μg/ml) of antimicrobial agent was:
|
No. of strains classified as S/I/Ra | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.03 | 0.06 | 0.12 | 0.25 | 0.5 | 1.0 | 2.0 | 4.0 | 8.0 | 16 | ||
| Penicillin (0.03-16.0) | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15/0/0 |
| Amoxicillin (0.03-8.0) | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15/0/0 | |
| Cefotaxime (0.06-8.0) | 4 | 6 | 5 | 0 | 0 | 0 | 0 | 0 | 15/0/0 | ||
| Cefuroxime (0.25-4.0) | 7 | 5 | 3 | 0 | 0 | 15/0/0 | |||||
| Meropenem (0.06-2.0) | 13 | 0 | 0 | 0 | 1 | 1 | 0 | 13/0/2 | |||
| Erythromycin (0.03-64.0) | 2 | 3 | 8 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 15/0/0 |
| Clindamycin (0.03-4.0) | 2 | 0 | 4 | 6 | 3 | 0 | 0 | 0 | 12/3/0 | ||
| Trimethoprim (0.12-8.0) | 0 | 1 | 3 | 9 | 1 | 1 | 0 | 13/2/0 | |||
| Levofloxacin (0.5-16) | 1 | 8 | 0 | 1 | 1 | 4 | 9/1/5 | ||||
| Sparfloxacin (1.0-2.0) | 15 | 0 | 15/0/0 | ||||||||
| Ciprofloxacin (2.0-8.0) | 9 | 1 | 5 | 9/1/5 | |||||||
| Chloramphenicol (2.0-16.0) | 13 | 2 | 0 | 13/2/0 | |||||||
| Vancomycin (0.12-2.0) | 5 | 10 | 0 | 0 | 0 | 15/0/0 | |||||
| Quinupristin-dalfopristin (1.0-2.0) | 15 | 0 | 15/0/0 | ||||||||
| Rifampin (2.0) | 15 | 15/0/0 | |||||||||
| Linezolid (2.0-4.0) | 15 | 0 | 15/0/0 | ||||||||
| Tetracycline (2.0-8.0) | 15 | 0 | 0 | 15/0/0 | |||||||
a
S, I, and R, susceptible, intermediate, and resistant, determined by using the NCCLS interpretive criteria for streptococci other than S. pneumoniae except for SXT and rifampin, for which the standards for S. pneumoniae were used.