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Binding data showing high selectivity of HS028 for the MC4 receptor beyond the other MC receptors. Competition curves of HS028 obtained on COS-1 cells transfected with the MC receptor clones, obtained by using a fixed concentration of [125I]-NDP-MSH and varying concentrations of the non-labelled competing peptide. Competing peptides used are indicated on abscissa for each panel. Each experiment were performed in duplicates and repeated three times.
