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Graphical representation showing KB values derived for the aliphatic series of α-substituted phenylglycine analogues when used with mGlu1α receptor- and mGlu5a receptor-expressing cells. KB values were derived from EC50 values calculated from dose responses carried out in the absence and presence of 1 mM of each antagonist. Results are means±s.e.mean from three independent experiments carried out on each cell line.
