Figure 4.

Effect of replacement by BTD at positions 19,20 and 33,34 in hα CGRP_8–37 on hα CGRP responses in rat prostatic vas deferens. Graph (left) showing a concentration response curve to hα CGRP on twitch responses, and in the presence of hα CGRP_8–37 BTD^{19,20 and 33,34} at 3×10⁻⁶M and 10⁻⁵M. The Schild plot (right) for hα CGRP_8–37 BTD^{19,20 and 33,34} against hα CGRP. Results on the graph are expressed as percentage inhibition of twitch responses. Points and error bars represent the mean±s.e.mean of four separate experiments. On the Schild plot, points represent individual data of eight separate experiments.