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. 1999 Mar;126(6):1341–1350. doi: 10.1038/sj.bjp.0702431

Figure 1.

Figure 1

Dependence of the rise in [Ca2+]i on BK, Lys-BK, and [desArg9]-BK concentrations. Confluent cultures of TECs on glass coverslips were loaded with 5 μM Fura-2/AM and fluorescent measurement of [Ca2+]i was carried out in a dual excitation wavelength spectrophotometer, with excitation at 340 and 380 nm. The log concentration-effect curves of the BK agonists, BK-, Lys-BK-, and [desArg9]-BK-induced rising in [Ca2+]i were derived from six separate experiments. Results represent the mean±s.e.mean as the increase above the resting level (210±15 nM).