Figure 4.

Interaction between TEA and verapamil block. Superimposed current traces at +80 mV with 45 mM TEA in the pipette and 100 μM external verapamil, recorded immediately after the rupture of the patch membrane (trace indicated as `Verapamil') and after 13 min (indicated as `TEA+Verapamil'), a time sufficient for the pipette solution to fully equilibrate with the cytoplasm. To afford a better comparison of current decay rates, the `TEA+Verapmil' trace has been scaled (2.3 times) to match the peak current of the `Verapamil' trace. TEA decreases the rate of verapamil-induced current decay from 0.083–0.031 ms⁻¹