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. 1999 May;127(1):57–64. doi: 10.1038/sj.bjp.0702504

Figure 6.

Figure 6

Failure of pitrazepin to antagonize the potentiating effect of flunitrazepam. (A) In an oocyte expressing α1β2γ2S GABAA receptors GABA 6 μM (left) activated inward Cl−-currents of comparable amplitude elicited by GABA 10 μM in the presence of 0.1 μM pitrazepin (right). Co-application of flunitrazepam 0.3 μM in both experimental condition determined a similar potentiation of Cl−-currents. (B) Potentiation of GABA-currents by flunitrazepam. Each column shows the mean±s.e.mean of current amplitude from six oocytes.