Figure 4.
Effects of cilostamide, Ro20-1724 and EHNA on the current-voltage and inactivation relationships of ICa in a rat ventricular myocyte. (A) current-voltage relationships and (B) inactivation curves for ICa obtained in the experiment shown in Figure 3 in control (squares), in the presence of 0.1 μM cilostamide and 0.1 μM Ro20-1724 (Cil+Ro, circles), and in the presence of 0.1 μM cilostamide, 0.1 μM Ro20-1724 and 10 μM EHNA (Cil+Ro+EHNA, triangles). Inactivation curves were obtained using a double-pulse protocol indicated in the inset and described in Methods.