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Effects of GABA on the renal nerve stimulation (RNS)-induced changes in perfusion pressure (PP) and noradrenaline efflux (NA Efflux) in the presence of bicuculline (A; Group 5, n=6) or 2-hydroxysaclofen (B; Group 6, n=6) in the isolated pump-perfused rat kidney. Δ, changes from basal values in response to RNS. Bicuculline (50 μM), 2-hydroxysaclofen (50 μM) and GABA (10 μM) were infused into the perfusate at 0.05 ml min−1. *P<0.01 compared with each control value.
