Figure 6.
Effect of tranilast on mRNA expression in VEGF-stimulated BREC. Effect of tranilast on integrin αv (a) and c-fos (b) mRNA expression in VEGF-stimulated BREC for 4 h. Typical autoradiograms of Northern blot analysis of BREC mRNA (top) and quantitation of multiple experiments after normalization to the control signal (bottom) are shown. Data are shown mean±s.e.mean of three experiments. Statistically significant difference compared with responses in the absence of tranilast, *P<0.001, **P<0.0001.