Figure 3.

Effects of nociceptin on scopolamine-induced impairment of spontaneous alternation (A) and total arm entries (B) in the Y-maze. Mice were treated with scopolamine (1.65 μmol kg⁻¹, s.c.) and nociceptin (0.5–5.0 nmol mouse⁻¹, i.c.v.) 30 min before the test. The data are expressed as median and interquartile ranges. Figures in parentheses show the numbers of mice used. ^**P<0.01 vs control for scopolamine alone (Mann-Whitney U-test), #P<0.05 vs scopolamine alone (Bonferroni's test).