Figure 1.

Modifications by L-NOARG (10 μM, 5 in the parenthesis) and L-NOARG plus L-arginine (L-Arg., 1 mM) (left figure) and by indomethacin (1 μM) (right) of the relaxant response to acetylcholine in corpus cavernosum strips contracted with phenylephrine. The ordinate represents relaxations relative to those induced by 0.1 mM papaverine. Significantly different from the value with L-NOARG, ^aP<0.01; ^bP<0.05 (Tukey's test). ‘n' denotes the number of strips from separate dogs. Vertical bars represent s.e.mean.