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. 2003 May 7;4:18. doi: 10.1186/1471-2164-4-18

Figure 2.

Figure 2

Sequence comparison of the human and murine ABHD1 proteins with two other closely related human ABHD proteins. The species are; Homo sapiens, Hs and Mus musculus, Mm. The proteins are human ABHD1; murine ABHD1 [25]; the putative transmembrane protein, HS1-2, ABHD2 [35] and the ORF of clones 23649 and 23755, accession No. AAC19155 truncated to first methionine residue, ABHD3 [36]. The stop codons are indicated by red asterisks. The predicted amino-terminus transmembrane domains are shown underlined. The predicted alpha/beta hydrolase fold domain is shown by a continuous blue line above the alignment and the predicted catalytic triads (which on human ABHD1 it is Ser203, Asp329 and His358) are indicated in bold and highlighted in green. The locations of the exon/exon boundaries are shown on the protein sequences as underlined residues. Residues conserved in all proteins are indicated by an (*), strongly conserved residues by (:) and weakly conserved residues by (.). Residues are colour coded: basic, DE, red; acidic, KR, pink; polar, CGHNQSTY, green and hydrophobic, AFILMPVW, red.