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. 1999 Jul;127(5):1213–1223. doi: 10.1038/sj.bjp.0702642

Figure 4.

Figure 4

Effect of 0.1 μM E-4031 on holding current and deactivation currents. (A) Pen record showing slow increase of outward current upon changing the holding potential to −20 mV (c.f. Schmitt & Meves, 1993), reversible reduction of holding current by 0.1 μM E-4031 and pulse families recorded before, during and after application of E-4031. (B) Currents elicited by pulse families in control, in E-4031 and after wash; pulse potentials −105 to −25 mV in steps of 10 mV, pulse duration 1 s. Cell diameter 53 μm. Temperature 34.5°C.