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. 1999 Jul;127(5):1213–1223. doi: 10.1038/sj.bjp.0702642

Figure 8.

Figure 8

Linopirdine and bradykinin inhibit ERG inward currents recorded in bath with 40 mM K+ at 33.5–35°C. (A) Currents recorded with the pulse programme shown in the inset: Holding potential −20 mV, two 0.5 s prepulses (to +20 and 0 mV, respectively), 160 ms pulses, pulse potentials −120 to 0 mV in 10 mV steps. (B) Peak current vs pulse potential in control, 50 μM linopirdine and wash. (C) Effect of 50 μM linopirdine on peak current; same pulse (V=−120 mV) applied every 30 s; inset shows currents at 1.5 and 7 min. (D) Effect of 1 μM bradykinin on peak current; same pulse (V=−120 mV) applied every 20 s; inset shows currents at 100 and 200 s.