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. 1999 Aug;127(7):1657–1665. doi: 10.1038/sj.bjp.0702678

Figure 2.

Figure 2

Inhibition of the physostigmine-induced pressor response in normotensive Wistar-Kyoto (open circles) and spontaneously hypertensive (closed circles) rats by various doses of the non-selective muscarinic receptor antagonist atropine (2A, 1.5–15 nmoles i.c.v., n=6) and the selective muscarinic receptor antagonists: pirenzepine (2B, 6–50 nmoles i.c.v., n=6), methoctramine (2C, 1.4–14 nmoles i.c.v., n=6), p-F-HHSiD (2D, 10–100 nmoles i.c.v., n=6) and tropicamide (2E, 1.5–15 nmoles i.c.v., n=6). Values are expressed as means±s.e.mean. Statistical significance versus the normotensive group: *P<0.05; **P<0.01; ***P<0.001 (Student's t-test).