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Distribution of curvatures in the yeast (top) and randomised yeast (bottom) data with Tcor = 0.6. Top: the mean curvature is 0.387 and 85% of nodes have positive curvature, bottom: cumulative distribution of curvatures after 1000 permutations in each of the 6221 genes. The proportion of nodes with non-zero curvature is 5 × 10-5
