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Time-dependent effects of PMA on 2MeSATP- and UTP-induced [3H]-IP formation in CPAE cells. Cells were pretreated with PMA (1 μM) for different periods of time before challenge with 100 μM 2MeSATP (□) or 100 μM UTP (⋄). Results are expressed as the mean±s.e.mean of three independent experiments. *Using ANOVA followed by Dunnetts test, P<0.05 was considered significant as compared to the 2MeSATP- or UTP-induced PI turnover without PMA pretreatment.
