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. Author manuscript; available in PMC: 2006 Sep 14.
Published in final edited form as: J Comp Neurol. 2005 Jun 20;487(1):75–92. doi: 10.1002/cne.20532

TABLE 6.

Relative Comparison of CRFR2 Binding across Six Species: Semiquantitative Analysis

Region Meadow Prairie Montane Pine Rat1 Monkey2
Choroid plexus +++++ +++++ +++++ +++++ +++++ +++++
Dorsal raphe ++++ ++++ ++++ +++++ +++ ++
Olfactory bulb ++ ++ + ++ +++ nr
Cortex ++ ++ + + + +
Amygdala ++ ++ + + +++ +++
Periaqueductal gray ++ ++ 0/+ + + nr
Locus coeruleus ++ ++ 0/+ + 0 0
Cerebellum ++ ++ 0/+ + 0 0
Lateral septum ++++ +++ ++++ +++++ ++++ +
Hippocampus ++++ ++ + + + +++
Laterodorsal thalamus 0 0 ++++ 0/+ 0 nr
Superior colliculus ++ ++ + + 0 nr
Nucleus accumbens, septal pole ++ ++++ + +++++ 0 nr
1

Rat data are compiled from meta-analysis of CRFR2 receptor binding reports from de Souza et al. (1987), Primus et al. (1997), Rominger et al. (1998), and Steckler and Holsboer (1999).

2

Monkey data are summarized from Sanchez et al. (1999) and Grigoriadis et al. (1995).

For vole data, averaged across sex: 0, <1000 dpm/mg; +, 1000–2000 dpm/mg; ++, 2000–4000 dpm/mg; +++, 4000–6000 dpm/mg; ++++, 6000–10000 dpm/mg; +++++, > 10000 dpm/mg; nr, not reported.