Table 3.

Potentiation of the pentobarbital sleep with carbenoxolone in mice

Treatment	Dose	Latency (min)	Duration (min)
Normal saline	10 ml/kg	7.28 ± 2.09	28.01 ± 1.88
Diazepam	1 mg/kg	4.67 ± 0.43**	49.16 ± 4.67***
Carbenoxolone	100 mg/kg	4.33 ± 0.25**	65.55 ± 5.06***
	200 mg/kg	4.24 ± 0.31**	75.10 ± 7.34***
	300 mg/kg	3.63 ± 0.38***	93.32 ± 16.49***

Carbenoxolone and diazepam (i.p.) were injected 60 and 30 minutes respectively, before pentobarbital (30 mg/kg) respectively. Mean latency and duration of sleep in minutes ± SEM from 10 mice in each group. **P < 0.01, ***P < 0.001, compared to control, Tukey-Kramer test.