Table 4.
Effect of Carbenoxolone on muscle relaxant activity by traction test
| Treatment | Dose | % failure |
| Normal saline | 10 ml/kg | 0 |
| Diazepam | 0.125 mg/kg | 0 |
| 0.25 mg/kg | 50* | |
| 0.5 mg/kg | 100*** | |
| Carbenoxolone | 200 mg/kg | 20 |
| 300 mg/kg | 40 | |
| 400 mg/kg | 60** |
Carbenoxolone and diazepam (i.p.) were injected 60 and 30 minutes respectively, before the test. Values are the mean ± SEM for 10 mice, *P < 0.05, **P < 0.01, ***P < 0.001, Compared to control, Fisher's exact test (two sided)