Table 3.

Adjusted health-related quality of life measures, stratified by CD4 count (N = 3772)

Disability Measure	CD4 <200 (n = 1950) (reference)		CD4 200–499 (n = 812)		CD4 ≥ 500 (n = 259)		CD4 Unknown (n = 751)
	mean	95% CL	mean	95% CL	mean	95% CL	mean	95% CL
Overall Health	45.5	42.7–48.2	56.8a	53.7–59.9	64.7b,c	60.3–69.0	49.4	46.2–52.7
Pain	61.8	58.6–65.0	67.6	64.0–71.2	71.6c	66.6–76.6	64.8	61.0–68.5
Physical Functioning	56.6	53.4–59.7	70.7a	67.2–74.2	78.1c	73.2–83.1	67.0	63.3–70.7
Role Functioning	41.3	37.0–45.6	61.9a	57.0–66.7	74.9b,c	68.0–81.7	58.3	53.2–63.4
Social Functioning	61.8	58.7–64.9	75.3a	71.8–78.8	84.3b,c	79.4–89.1	70.5	66.9–74.2
Mental Health	57.1	54.8–59.3	59.1	56.5–61.6	61.1	57.5–64.6	58.7	56.0–61.3
Energy/Fatigue	45.4	43.0–47.7	53.3a	50.6–55.9	58.8c	55.0–62.5	49.8	47.0–52.6
Cognitive Functioning	71.0	68.6–73.4	74.2	71.5–76.9	76.4	72.7–80.2	78.0	75.2–80.8

least-squares means analysis; Tukey-Kramer adjustment for multiple comparisons; significance level P<0.05;

^* includes 318 persons who never had a CD4 test

^a significant pairwise difference: CD4 < 200 vs. CD4 200–499;

^b significant pairwise difference: CD4 200–499 vs. CD4 ≥ 500;

^c significant pairwise difference: CD4 < 200 vs. CD4 ≥ 500;

CL= confidence limit

factors in model: age, education, sex, race/ethnicity, HIV risk, health insurance status, income time known HIV+, current antiretroviral status, type of recruitment