Table 2.
CCQ scores in subgroups (Healthy, At Risk and COPD (Stage I-III))
| COPD | ||||||
| CCQ | Healthy (ex)smokers | At Risk (Stage 0) | Mild (Stage I) | Moderate A(Stage IIA) | Moderate B (Stage IIB) | Severe (Stage III) |
| Symptom | 1.5a | 3.3b | 1.8a,c | 2.0c,d | 3.1b,d | 2.9,b,c |
| (0.3–3.5) | (1.8–5.3) | (0.5–5.0) | (0.8–5.3) | (0.8–4.5) | (1.5–4.5) | |
| Functional | 0.8a | 1.4b,c | 0.3a | 1.4b | 1.5b | 2.6c |
| state | (0.0–3.8) | (0.3–6.0) | (0.0–2.5) | (0.3–4.0) | (0.5–4.8) | (2.0–5.0) |
| Mental state | 0.0a | 0.0a,b | 0.0a | 0.0a,c | 1.0b | 0.5b,c |
| (0.0–3.0) | (0.0–3.5) | (0.0–1.0) | (0.0–4.5) | (0.0–5.0) | (0.0–3.0) | |
| Total | 0.8a | 2.0b,c | 1.0a,d | 1.3b,d | 1.9b,c | 2.5c |
| (0.1–3.3) | (0.8–5.2) | (0.2–2.5) | (0.5–4.3) | (0.9–4.7) | (1.7–4.3) | |
CCQ = Clinical COPD Questionnaire; range 0 – 6; 0 indicating best possible clinical control and 6 indicating worst possible clinical control. Medians not sharing a common superscript letter (a,b,c,d) are significant different at p < 0.05 after Mann-Whitney U test. Healthy (ex) smokers; normal spirometry, no chronic symptoms (cough, sputum production). COPD classification of COPD by severity according to the GOLD guidelines; Stage 0: normal spirometry, chronic symptoms (cough, sputum production); Stage I: FEV1/FVC < 70%, FEV1 ≥ 80 % predicted, with or without chronic symptoms (cough, sputum production, dyspnea); Stage IIA: FEV1/FVC < 70%, 50% ≥ FEV1 < 80 % predicted; Stage IIB: FEV1/FVC < 70%, 30% ≥ FEV1 < 50 % predicted; Stage III: FEV1/FVC < 70%, FEV1 < 30 % predicted or FEV1 < 50% predicted plus respiratory failure or clinical signs of right heart failure.