Table 1. NOEs between distamycin and [TAGGGTTA]₄ DNA^a.

Distamycin group	δ (p.p.m.)	NOEs to [TAGGGTTA]4b
Pyrrole CH3-1	3.51	A2 H2, A2 H8,
		G5 H1, G5 H1′, A8 H2, T6 CH3
Pyrrole CH3-2	3.49	T1 H1′,
		G5 H1, G5 H8, T6 H6, T7 H1′, T7 H6
Pyrrole CH3-3	3.59	G3 H8,
		G5 H1′, G5 H8, A8 H2, T7 CH3
Pyrrole H3-1, H3-2	6.34	T1 CH3,
		T6 CH3, T6 H1′, T7 H1′
Pyrrole H3-3	6.51	T1 CH3,
		G5 H1′, T6 CH3, T6 H1′, T6 H2′, T7 H1′
Pyrrole H5-1	6.77	T1 CH3,
		T6 CH3, T6 H2′
Pyrrole H5-2	6.71	T6 CH3, T7 CH3
Pyrrole H5-3	6.80	T6 H1′, T7 CH3
Formyl HF	7.84	T1 CH3,
		T6 CH3

^aNOESY τ_m = 250 ms, 35°C, D₂O, molar ratio of 4:1 distamycin to G4 DNA molecule.

^bFour additional weak NOEs exist between distamycin H3 and H5 protons and overlapping DNA deoxyribose protons.