Fig. 1.
Sequence alignment of T. maritima FliM, CheC, CheX, and FliY. Secondary structural elements of FliM are more similar to CheC than to CheX, especially in the regions of α2/βx and α2′/βx′ (red). Conserved solvent-exposed FliM residues (yellow) occur at different positions than those of the CheC/CheX/FliY phosphatase family (boxed), with the exception of α1 residues. Solvent-exposed residues that are conserved differently by two general families of chemotactic bacteria (32) indicate potential sites for protein–protein interactions (highlighted in orange).