Table 2.

Thermodynamic parameters for residues of Groups 1, 2, and 3

Group	Forward		Reverse		Equilibrium		Barrier ΔG+ at 22°C, kJ/mol
	ΔH+, kJ/mol	ΔS+, J/mol·K	ΔH+, kJ/mol	ΔS+, J/mol·K	ΔH, kJ/mol	ΔS, J/mol·K	Forward	Reverse
1	74 ± 5	24 ± 15	67 ± 7	41 ± 24	7 ± 5	−17 ± 16	66.7 ± 0.1	54.8 ± 0.1
2	67 ± 1	15 ± 4	71 ± 6	46 ± 20	−5 ± 6	−30 ± 21	62.3 ± 0.1	58.0 ± 0.1
3	41 ± 2	−66 ± 7	62 ± 2	20 ± 6	−21 ± 1	−87 ± 4	60.1 ± 0.1	55.5 ± 0.1

See the Table 1 legend for an explanation of Groups 1–3.