Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Impact of PAIs on virulence of strain 536 in infant murine model of ascending UTI
| Strain used for infection | LD50 |
|
|---|---|---|
| cfu/ml* | Change† | |
| 536 wild type | 4.89 × 103 | – |
| 536ΔPAI I (536-114) | 3.46 × 106 | 709 |
| 536ΔPAI II (536-225) | 4.57 × 106 | 935 |
| 536ΔPAI III | 2.23 × 106 | 456 |
| 536ΔPAI IV | 1.66 × 103 | 0.34 |
| 536ΔPAI V | 8.25 × 103 | 1.69 |
| 536ΔPAI IΔPAI II (536-2I) | >109 | >2 × 105 |
*Approximately 25 μl of inoculum was injected into the bladder of mice.
†Relative fold increase compared with the wild-type strain.
