Table 3.
Liposome inhibitors protect rats from LeTx challenge
Treatment | Moribund rats/total |
---|---|
LeTx | 5/6 |
LeTx + 400 nmol inhibitor | 0/6 |
LeTx + thioglycerol-functionalized liposomes | 6/6 |
Rats were injected intravenously with only LeTx (30 μg of PA and 8 μg of LF), LeTx with thioglycerol-functionalized liposomes or LeTx with liposome inhibitors. The amount of inhibitor is listed in terms of amount of peptide. Results are combined from two independent experiments and are statistically significant by the log-rank test.