Table 1.

Microarray analysis of RovA regulon in Y. pestis

Identification	ORF description	Fold change
		Array*	qRT-PCR†
YPO0499‡	Hypothetical protein	−4.6	−4.4
YPO0506‡	clpB/htpM putative Clp ATPase	−5.5	−3.1
YPO0510‡	Hypothetical protein	−4.6	−5.3
YPO0514‡	Putative OmpA-family protein	−4.4	−3.6
YPO1301	psaE, putative regulatory protein	−5.7	−9.8
YPO1302	psaF, putative membrane protein	−4.7	−11.3
YPO1303	psaA, pH 6 antigen	−25.9	−133
YPO1304	psaB, chaperone protein	−8.7	−66.5
YPO2277§	Phage hypothetical protein	23.2	66.7

Shown is a partial list of genes from the microarray analysis that were ≥2-fold different with a P value of ≤0.05, as described in Materials and Methods. A complete list of regulated genes from the array can be found in the supporting information.

*Fold difference in gene transcripts between wild type and the ΔrovA mutant as determined by microarray analysis.

^†Fold difference in gene transcripts between wild type and the ΔrovA mutant as determined by qRT-PCR. The value listed is the average fold difference from multiple repeats of qRT-PCR performed on different biological replicates, as described in Materials and Methods.

^‡IAHP locus (29, 30).

^§Cus-2 phage locus (34).