Figure 9.

Alteration of the Ca²⁺ signal in cells defective in ${\text{O}}_2^{·-}$ generation. The fMLP-induced Ca²⁺ signal was compared in differentiated PLB-985 myeloid cells containing an intact NADPH oxidase or no functioning enzyme (marked CGD) (a) and in peripheral blood neutrophils inhibited by 5 μM DPI (fMLP+DPI) or investigated in the absence of inhibitor (fMLP only) (b). This figure was originally published by Rada, B. K., Geiszt, M., van Bruggen, R., Német, K., Roos, D., & Ligeti, E. 2003 Clin. Exp. Immunol. 132, 53–60. © the British Society of Immunology.