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. 2006 Aug;173(4):2257–2267. doi: 10.1534/genetics.105.047472

TABLE 2.

Estimates of ρ

Type ρ0 = 20 ρ0 = 40 ρ0 = 60
Modifieda (25, 0.90, 0.85) (46, 0.57, 0.91) (63, 0.38, 1.0)
Modifiedb (25, 1.1, 0.81) (43, 0.62, 0.89) (59, 0.41, 1.0)
Modifiedc (27, 1.1, 0.79) (48, 0.62, 0.88) (65, 0.40, 1.0)
Simpleb (27, 1.2, 0.80) (44, 0.60, 0.89) (57, 0.41, 1.0)
Simplec (3, 0.85, 0.99) (16, 0.77, 0.98) (41, 0.56, 1.0)
Realb (22, 1.1, 0.84) (38, 0.62, 0.91) (50, 0.46, 1.0)
Realc (20, 0.95, 0.87) (37, 0.60, 0.94) (52, 0.46, 1.0)

The three numbers within the parentheses denote the mean, the root (relative) mean square error, and probability that the estimate falls within a factor of two of the true parameter, respectively. Three combinations of (sensitivity, specificity) are examined:

a

(1.0, 1.0).

b

(0.34, 1.0).

c

(0.68, 0.75).