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. 2006 Aug;173(4):2257–2267. doi: 10.1534/genetics.105.047472

TABLE 4.

Model misspecification effect in dependent model with 3.3% probe coverage

Inference
Simulation (0.34, 1.0) (1.0, 1.0) (0.68, 0.75)
a. True θ = 200
(0.34, 1.0) (204, 0.46) (609, 2.2) (987, 3.9)
(1.0, 1.0) (60, 0.71) (201, 0.27) (446, 1.2)
(0.68, 0.75) (14, 0.92) (8, 0.96) (207, 0.54)
Inference
Simulation True (sn, sp) (0.5, 0.98)
b. True ρ = 20
(0.34, 1.0) (25, 1.2, 0.81) NA
(1.0, 1.0) (25, 0.90, 0.85) (25, 0.91, 0.85)
(0.68, 0.75) (27, 1.1, 0.79) (22, 0.80, 0.88)

Test data are generated with sensitivity and specificity listed in the Simulation column and estimates are listed under different (sn, sp) used in Inference. See text for details. Notation in a is the same as in Table 1 and notation in b is the same as in Table 2.