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LOD curves from the B6CASTF2 Xce heterozygotes/Xce homozygotes whole-genome scan. LOD score is on the y-axis; chromosomes are on the x-axis. Genetic location of markers tested are indicated by tick marks on the x-axis. The genomewide level of significance as determined by permutation tests is LOD = 3.5. Significance was reached only on the X chromosome, indicating that Xce is the only major locus influencing X inactivation patterns in this cross.
