Figure 3.—

Haplotype map of females with crossovers between DXMit41 and DXMit171. Heterozygous genotypes (B6/CAST or BALB/CAST) are indicated as shaded segments; homozygous genotypes (B6/B6 or BALB/BALB) are indicated as solid segments. Diagonal regions between markers indicate the location of crossover events. The locations of Xite, Tsix, and Xist are indicated. The genetic background and X inactivation pattern of each individual are also indicated. Animals with homozygous genotypes between SNP-846 and DXMit171 had Xce homozygous-like X inactivation patterns, suggesting that the proximal boundary of the Xce interval lay between DXMit168 and SNP-846. Conversely, animals with heterozygous genotypes between DXMit41 and SNP-843 had Xce heterozygous-like X inactivation patterns, suggesting that the distal boundary of the candidate interval lay between LeeSNPG-I and SNP-843. The B6CAST N4 backcross individual selected for further progeny testing (Figure 4) is indicated by an arrowhead.