TABLE 3.

Apportionment of genetic variation in HLA loci and microsatellites

	HLAa					Microsatelliteb
	A	B	C	DRB1	DQB1	CDP (I)c	CDP (II)d	95% C.I. (I)	95% C.I. (II)
Among regions (%)	7.41	2.98	3.55	7.47	7.00	5.63	5.62	0.51–14.92	−1.55–18.73
Among populations within region (%)	3.87	4.22	4.55	4.42	5.21	2.67	4.92	0.38–6.08	0.69–12.03
Within populations (%)	88.71	92.80	91.90	88.11	87.79	91.70	89.46	81.67–97.57	77.10–96.64

Values refer to the percentage of the total variance attributable to differences at that hierarchical level.

^aThe HLA class I data consist of the 19 non-Australian populations assigned to the regions given in Table 1. The class II data consist of 13 of the 15 non-Australian populations as described in Methods and Figure 3.

^bThe microsatellite data consist of samples from the 38 CEPH Diversity Panel (CDP) populations that could be assigned to the geographic regions for the HLA data.

^cNineteen populations were sampled from the 38 CDP populations to match the HLA class I distribution of populations. Values are averaged over results for 1000 repeated samples.

^dThirteen populations were sampled from the 38 CDP populations in order to match the HLA class II distribution of populations. Values are averaged over results for 1000 repeated samples.