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. 2006 Aug;173(4):2121–2142. doi: 10.1534/genetics.105.052837

TABLE 5.

Region-specific (RS) alleles

HLA class Ia
A
B
C
Region Proportion of RS allelesb Median relative freqc Proportion of RS allelesb Median relative freqc Proportion of RS allelesc Median relative freqc
ALLd 0.301 0.033 0.374 0.045 0.235 0.033
SSA 0.299 0.033 0.396 0.039 0.110 0.031
EUR 0.046 0.018 0.086 0.023 0.049 0.017
SEA 0.061 0.017 0.062 0.027 0.068 0.029
OCE 0.002 0.001 0.064 0.042 0.005 0.002
NEA 0.088 0.031 0.092 0.027 0.023 0.008
NAM 0.020 0.004 0.137 0.109 0.139 0.046
SAM 0.152 0.056 0.366 0.100 0.175 0.176
HLA class IIa
DRB1
DQB1
Region
Proportion of RS allelesb
Median relative freqc
Proportion of RS allelesb
Median relative freqc
ALLd 0.231 0.043 0.035 0.009
SSA 0.137 0.069 0.016 0.005
EUR 0.138 0.051 0.006 0.003
SEA 0.045 0.013 0.012 0.005
OCE 0.044 0.014 0.001 0.000
NAM 0.069 0.036 0.000 0.000
SAM 0.070 0.032 0.021 0.003
a

Results are averaged over 1000 different samples of size 20 from the IHW populations.

b

The percentage of alleles that are region specific.

c

The median relative frequency is computed as the median frequency of the RS alleles among all populations in the region where the RS alleles were found, including zero values for populations where a RS allele was not found.

d

Results for the entire data set.