TABLE 5.
Region-specific (RS) alleles
HLA class Ia
|
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---|---|---|---|---|---|---|
A
|
B
|
C
|
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Region | Proportion of RS allelesb | Median relative freqc | Proportion of RS allelesb | Median relative freqc | Proportion of RS allelesc | Median relative freqc |
ALLd | 0.301 | 0.033 | 0.374 | 0.045 | 0.235 | 0.033 |
SSA | 0.299 | 0.033 | 0.396 | 0.039 | 0.110 | 0.031 |
EUR | 0.046 | 0.018 | 0.086 | 0.023 | 0.049 | 0.017 |
SEA | 0.061 | 0.017 | 0.062 | 0.027 | 0.068 | 0.029 |
OCE | 0.002 | 0.001 | 0.064 | 0.042 | 0.005 | 0.002 |
NEA | 0.088 | 0.031 | 0.092 | 0.027 | 0.023 | 0.008 |
NAM | 0.020 | 0.004 | 0.137 | 0.109 | 0.139 | 0.046 |
SAM | 0.152 | 0.056 | 0.366 | 0.100 | 0.175 | 0.176 |
HLA class IIa
| ||||
---|---|---|---|---|
DRB1
|
DQB1
|
|||
Region
|
Proportion of RS allelesb
|
Median relative freqc
|
Proportion of RS allelesb
|
Median relative freqc
|
ALLd | 0.231 | 0.043 | 0.035 | 0.009 |
SSA | 0.137 | 0.069 | 0.016 | 0.005 |
EUR | 0.138 | 0.051 | 0.006 | 0.003 |
SEA | 0.045 | 0.013 | 0.012 | 0.005 |
OCE | 0.044 | 0.014 | 0.001 | 0.000 |
NAM | 0.069 | 0.036 | 0.000 | 0.000 |
SAM | 0.070 | 0.032 | 0.021 | 0.003 |
Results are averaged over 1000 different samples of size 20 from the IHW populations.
The percentage of alleles that are region specific.
The median relative frequency is computed as the median frequency of the RS alleles among all populations in the region where the RS alleles were found, including zero values for populations where a RS allele was not found.
Results for the entire data set.