TABLE 4.
Summary of recombination at A1-b and A1-b(P415)
α and β
|
Rate of recombination in the absence vs. presence of homolog | Preferred pairing partner with homolog | |||
---|---|---|---|---|---|
Haplotype | Order | Sequence identity (%) | Preferred template | ||
A1-ba | α-β-Sh2 | 96 | 10- to 13-fold lower | 94% paired with homolog | α |
A1-b(P415)a | β-α-Sh2 | 99.9 | 1.2-fold higher | NDb | NDc |
The rates of recombination in the presence of a homolog are similar between A1-b and A1-b(P415). In the absence of a homolog (i.e., in a hemizygote), however, the rate of recombination is ∼13-fold higher in A1-b(P415) as compared to A1-b.
The preferred template in the presence of a homolog could not be determined in A1-b(P415).
Because α and β are nearly identical, the pairing partner cannot be determined.