TABLE 2.

Correlations between genomic GC content and the frequency of GC-rich (GAPW) and GC-poor (FYMINK) amino acids in complete NPM proteins and discriminating between N-terminal and C-terminal domains

NPM lineage	Spearman rank correlation coefficient, rS	P-value
NPM1	Complete
GC fourfold vs. GAPW	0.018	0.839
GC fourfold vs. FYMINK	−0.216	0.726
	N terminus
GC fourfold vs. GAPW	0.131	0.569
GC fourfold vs. FYMINK	0.000	0.922
	C terminus
GC fourfold vs. GAPW	0.036	0.671
GC fourfold vs. FYMINK	0.668	0.454
NPM2	Complete
GC fourfold vs. GAPW	−0.571	0.095*
GC fourfold vs. FYMINK	−0.786	0.027**
	N terminus
GC fourfold vs. GAPW	−0.147	0.582
GC fourfold vs. FYMINK	−0.720	0.156
	C terminus
GC fourfold vs. GAPW	−0.927	0.009***
GC fourfold vs. FYMINK	−0.299	0.688
NPM3	Complete
GC fourfold vs. GAPW	0.559	0.046**
GC fourfold vs. FYMINK	−0.667	0.039**
	N terminus
GC fourfold vs. GAPW	0.404	0.396
GC fourfold vs. FYMINK	−0.118	0.909
	C terminus
GC fourfold vs. GAPW	0.134	0.875
GC fourfold vs. FYMINK	0.134	0.811

The asterisks indicate significance levels as *P < 0.1, **P < 0.05, ***P < 0.01.