TABLE 3.

Differences between the frequencies of the nucleotide adenine at second codon positions vs. the frequencies at fourfold degenerate positions in the functional domains of NPM genes

NPM lineage	t statistic	P-value
NPM1
N terminus	−5.343	1.032 × 10−4
C terminus	3.263	5.658 × 10−3
NPM2
N terminus	1.012	3.315 × 10−1
C terminus	3.566	3.879 × 10−3
NPM3
N terminus	2.615	2.259 × 10−2
C terminus	2.859	1.431 × 10−2