TABLE 3.
Rescue of the synthetic lethality of Nnd-p e(r)p2 males
Transgenea | Nnd-p e(r)p2; transgene/+ | Nnd-p e(r)p2; +/+ | FM7c | Transgenic/ nontransgenic | (Transgenic/nontransgenic) FM7c |
---|---|---|---|---|---|
e(r)+ | 83* | 7 | 237 | 11.9 | 0.32 |
T18A | 112* | 0 | 256 | — | 0.44 |
T18E | 59* | 2 | 104 | 29.5 | 0.55 |
S24E | 32* | 1 | 127 | 32.0 | 0.24 |
E27Q | 180* | 0 | 330 | — | 0.55 |
T63A | 155* | 0 | 138 | — | 1.12 |
T63E | 106* | 9 | 123 | 11.8 | 0.79 |
T18A-T63A | 311* | 74 | 641 | 4.2 | 0.37 |
T18E-T63E | 74* | 5 | 77 | 14.8 | 0.90 |
S24E-T63E | 195* | 18 | 257 | 10.8 | 0.69 |
T18A-S24A | 39*** | 21 | 152 | 1.9 | 0.12 |
T18E-S24E | 7**** | 9 | 290 | 0.8 | 0.0 |
T18A-S24A-T63A | 22** | 7 | 169 | 3.1 | 0.09 |
T18E-S24E-T63E | 94* | 53 | 406 | 1.8 | 0.10 |
The crosses used to generate these flies are explained in materials and methods. *Corrected chi-square P-value <0.001; **P-value <0.01; ***P-value <0.05; ****insufficient data to calculate P-value.
Data collected from one insert per construct: e(r)+, T18A, T18E, S24E, T18E-T63E; data collected from two inserts per construct: E27Q, T63A, T63E, T18A-S24A, T18A-S24A-T63A; data collected from three inserts per construct: S24E-T63E, T18E-S24E-T63E; data collected from four inserts per construct: T18E-S24E, T18A-T63A.