Figure 3.—

GET3 is coregulated with genes encoding components of the proteasome and the Cdc48-Npl4-Ufd1 complex. GET3 (thick box) is similarly expressed with many protein-degradation genes (boldface type) and genes encoding the Cdc48/Npl4/Ufd1 complex (thin boxes). The data set of expression profiling under various conditions from Eisen et al. (1998) was analyzed by hierarchical clustering using Average Link correlation (uncentered), and the GET3-containing cluster from analysis with TreeView software is shown. Treatments analyzed include cell cycle time courses, the diauxic shift, a time course during sporulation, and the altered expression of NDT80.