TABLE 2.

Comparison of APOE haplotype frequencies estimated from different methods

Haplotypes	EM-Parent	EM-Sib	EM-Single	GH-Sib	GH-Family	FAMHAP-Sib
CGTC	0.3721	0.3789	0.3855	0.3599	0.3939	0.3763
CGTG	—	0.0015	—	—	0.0058	—
CGCC	0.0094	0.0075	0.0010	0.0130	0.0044	—
CGCG	—	—	—	—	—	—
CATC	0.0018	0.0046	0.0069	0.0093	0.0087	0.0096
CATG	0.0013	—	—	—	—	—
CACC	—	—	—	—	—	—
CACG	—	—	—	—	—	—
GGTC	0.0272	0.0275	0.0409	0.1262	0.0392	0.0352
GGTG	0.0615	0.063	0.0508	0.0353	0.0538	0.0512
GGCC	0.1215	0.108	0.0979	0.0557	0.1279	0.1330
GGCG	0.0010	—	—	0.0130	—	—
GATC	0.3982	0.3953	0.4170	0.3210	0.3576	0.3914
GATG	0.0060	0.0055	—	0.0204	0.0044	0.0055
GACC	0.0001	0.0006	—	0.0464	0.0044	—
GACG	—	—	—	—	—	—
Discrepancy	—	0.0173	0.0511	0.1826	0.0573	0.0304

See Table 1 legend for details.